E-cigs have been on the market for 15 years: If they were really reducing harm it would be obvious by now

Ever since e-cigarettes first came on the market in 2006 the argument has been that it will take time for their health benefits to be manifest. This view was restated again last month in an FDA press release that stated, “Companies who want to continue to market their flavored ENDS products must have robust andContinue reading “E-cigs have been on the market for 15 years: If they were really reducing harm it would be obvious by now”

PMPSA’s supplemental modified risk tobacco product application for IQOS 3 does not support the conclusion that IQOS will not harm vascular endothelial function and does not address new published research, so FDA should not issue an exposure modification MRTP order for IQOS 3 support the conclusion that IQOS will not harm vascular endothelial function and does not address new published research, so FDA should not issue an exposure modification MRTP order for IQOS 3

My colleagues and I at the UCSF TCORS just submitted this public comment to the FDA. The tracking number on Regulations.gov is kta-aq6w-3tph. A PDF is available here. PMPSA’s supplemental modified risk tobacco product application for IQOS 3 does not support the conclusion that IQOS will not harm vascular endothelial function and does not addressContinue reading “PMPSA’s supplemental modified risk tobacco product application for IQOS 3 does not support the conclusion that IQOS will not harm vascular endothelial function and does not address new published research, so FDA should not issue an exposure modification MRTP order for IQOS 3 support the conclusion that IQOS will not harm vascular endothelial function and does not address new published research, so FDA should not issue an exposure modification MRTP order for IQOS 3”

New WHO report highlights falling cigarette use and challenges that new tobacco products pose to public health and implementation of the FCTC

On July 27, 2021 the WHO released the WHO report on the global tobacco epidemic 2021: addressing new and emerging products, its eighth such report. The good news is that it documents solid progress in reducing tobacco use. After over a century of growth, “between 2007 and 2019, smoking rates decreased from a global averageContinue reading “New WHO report highlights falling cigarette use and challenges that new tobacco products pose to public health and implementation of the FCTC”

We know a lot about how e-cigarettes cause disease

The evidence on the health effects of e-cigarettes was the subject of two recently published reviews that focus on cardiovascular, pulmonary and immunologic effects of e-cigarettes. These reviews complement earlier reviews on the pulmonary effects of e-cigarettes, e-cigarettes and smoking cessation, and the gateway effect for smoking among youth and young adults. Taken together theseContinue reading “We know a lot about how e-cigarettes cause disease”

The biological evidence of e-cig dangers keeps piling up

Rachel Keith and Aruni Bhatnagar just published “Cardiorespiratory and Immunologic Effects of Electronic Cigarettes,” which is a nice overview of the growing biological evidence base that e-cigarettes have a lot of adverse health effects, many similar to cigarettes. This material is particularly important because the people who continue to promote e-cigarettes for “harm reduction” continueContinue reading “The biological evidence of e-cig dangers keeps piling up”

Three years later the NASEM report on e-cigs is out of date

Physicians for a Smokefree Canada just released this blog post which is an excellent summary of how the state of knowledge has advanced substantially since the National Academies of Science, Engineering and Medicine released its report on e-cigarettes in 2018. While the report was a good summary of the evidence when it was prepared, weContinue reading “Three years later the NASEM report on e-cigs is out of date”

Smokefree law and tobacco tax increases followed by big drops in heart attacks in Thailand

The fact that smokefree laws are followed by reductions in hospitalization for heart attacks has been well-documented (page 435) in developed countries such as the U.S. and European countries. Thailand began implementing smoking restrictions in 1992 and then repeatedly updated them to expand smokefree places. In 2010, Thailand achieved 100% smokefree public places at theContinue reading “Smokefree law and tobacco tax increases followed by big drops in heart attacks in Thailand”

Smoking marijuana associated with higher heart disease and stroke risk

One of the difficulties in studying the epidemiological link between marijuana use and disease is the fact that most people who smoke marijuana also smoke cigarettes, making it hard to pry the effects apart in a statistical analysis. Siddarth Shah and colleagues just published an important analysis that avoids this problem by only studying neverContinue reading “Smoking marijuana associated with higher heart disease and stroke risk”

Major EU scientific committee highlights e-cig dangers, gateway effect

On 23 September 2020, the European Commissions’ Scientific Committee on Health, Environmental and Emerging Risks (SCHEER) issued its Preliminary Opinion on electronic cigarettes  at a request from the Commission “to assist the Commission in assessing the most recent scientific and technical information on e-cigarettes. Findings presented in the scientific opinion will feed into the Commission’sContinue reading “Major EU scientific committee highlights e-cig dangers, gateway effect”