Health groups back in court pressing FDA to act on menthol and e-cig PMTA applications

Menthol Over the last year health groups have started suing the FDA in efforts to force action, particularly in the areas of menthol and evaluating e-cigarettes and other new tobacco products. As part of a political compromise, the 2009 Family Smoking Prevention and Tobacco Control Act banned characterizing flavors (but not the flavors themselves) exceptContinue reading “Health groups back in court pressing FDA to act on menthol and e-cig PMTA applications”

Ecig use associated with about double the odds of erectile dysfunction

Cigarette smoking causes erectile dysfunction, a point highlighted in the California Tobacco Control Program’s 1998 ad, “Gala Event” (below). There are multiple pathways between smoking and erectile dysfunction, including adverse effects of nicotine, depression in testosterone, increased risk of cardiovascular and other disease and adverse effects on the ability of arteries to dilate (get larger).Continue reading “Ecig use associated with about double the odds of erectile dysfunction”

Vaping disrupts mitochondria and promotes inflammation independent of the effects of past smoking

The fact that many e-cigarette users are former or current cigarette smokers (dual users) complicates understanding the health effects of e-cigarette use.  Stella Tommasi, Ahmad Besaratinia and their colleagues at USC have used sophisticated genomic analysis of white blood cells (leukocytes) collected from people to pry these effects apart. In their paper, “A novel roleContinue reading “Vaping disrupts mitochondria and promotes inflammation independent of the effects of past smoking”

Vaping exploding among New Zealand youth

Like their British cousins, most public health authorities in New Zealand have embraced e-cigarettes for harm reduction. In contrast to heavily regulated cigarettes (no advertising, plain packaging, graphic warning labels, no power walls, strong smokefree laws), e-cigs were introduced to New Zealand in around 2017 without any regulations on marketing and advertising no controls onContinue reading “Vaping exploding among New Zealand youth”

47 countries have banned e-cigarettes

As tobacco industry interests ramp up pressure on the WHO Framework Convention on Tobacco Control Conference of the Parties to embrace e-cigarettes and the industry’s harm reduction marketing frame, it is important to keep in mind that many countries have rejected e-cigarettes and other ENDS completely. Here is a list that Clear the Air HongContinue reading “47 countries have banned e-cigarettes”

E-cig inventor Hon Lik is still smoking

Popular lore is that Chinese pharmacist Hon Lik invented e-cigarettes in 2003 to help people quit smoking. The Times of London reported that it didn’t work for him. Instead of “switching completely” he is a dual user, vaping and smoking at the same time. Hon Lik’s experience is what you would expect from the strongContinue reading “E-cig inventor Hon Lik is still smoking”

New meta-analysis confirms that e-cigs do not help smokers quit in the real world

Linnea Hedman and colleagues in Sweden just published a new meta-analysis of the relationship between e-cigarette use and smoking cessation, Electronic cigarette use and smoking cessation in cohort studies and randomized trials: A systematic review and meta-analysis. Like our earlier meta-analysis, did separate analyses of population-based observational studies and randomized trials of e-cigarettes provided asContinue reading “New meta-analysis confirms that e-cigs do not help smokers quit in the real world”

World Heart Federation highlights cardiovascular risks of e-cigs, calls for strict regulation, supports countries with bans

On October 18, 2021 the World Heart Federation released a policy brief “E-cigarettes: A new threat to cardiovascular health,” (press release) that provides an overview of the evidence that e-cigarette use has a wide range of adverse effects on the cardiovascular system that are reflected as an increased risk of heart attack at a populationContinue reading “World Heart Federation highlights cardiovascular risks of e-cigs, calls for strict regulation, supports countries with bans”

Science FDA (and everyone else) needs to actively engage as they think about whether to authorize Juul and the other ecigs

When I read the FDA’s Technical Project Lead summary of its scientific justification for authorizing the sale of RJ Reynolds’ Vuse Solo e-cigarette, I was struck by the fact that it ignored the broad scientific literature on e-cigarettes and seemed to accept industry-framed arguments. For example: They ignored the evidence that as consumer products, e-cigarettesContinue reading “Science FDA (and everyone else) needs to actively engage as they think about whether to authorize Juul and the other ecigs”

E-cigarettes don’t help smokers stay off cigarettes

Last week the FDA authorized the sale of RJ Reynolds’ (BAT’s US subsidiary) Vuse e-cigarette despite heavy use by kids because “the manufacturer’s data demonstrates its tobacco-flavored products could benefit addicted adult smokers who switch to these products – either completely or with a significant reduction in cigarette consumption – by reducing their exposure toContinue reading “E-cigarettes don’t help smokers stay off cigarettes”