Chen Chen and colleagues recently published Assessing the association between e-cigarette use and cardiovascular disease: A meta-analysis of exclusive and dual use with combustible cigarettes that found significantly elevated cardiovascular disease risk in dual users (people who use both e-cigarettes and cigarettes) and former smokers who had switched to e-cigarettes compared to people who hadContinue reading “New meta-analysis of e-cigs and cardiovascular disease shows increased risks”
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Tobacco free generation is a bad idea that should be abandoned
In the last few years the idea of a free generation in which tobacco sales would be prohibited to all people born after a certain date has gained some traction. Ever since the idea was first proposed by some Singapore researchers in 2010, I have thought it was a bad idea. Other than declining toContinue reading “Tobacco free generation is a bad idea that should be abandoned”
Smoking gun document ties Al Sharpton to Juul, efforts to protect menthol cigs
Fenit Nirappil’s comprehensive Washington Post story How Black activists became defenders of Big Tobacco (June 21, 2024) includes the 2018 smoking gun document linking Al Sharpton the African American leader who played a key role in convincing Biden to pull FDA regulations ending menthol cigarettes and flavored cigars, as well as other African American andContinue reading “Smoking gun document ties Al Sharpton to Juul, efforts to protect menthol cigs”
Shocking FDA TPSAC Meeting on PMI General Snus modified risk application
I spoke at the FDA Tobacco Products Scientific Advisory Committee meeting held yesterday (June 26, 2024) to consider Philip Morris International’s (PMI) Modified Risk Tobacco Product (MRTP) application to renew authorization to make modified (read “reduced”) risk claims about its Swedish Match General Snus. I expected the meeting to end with TPSAC voting on aContinue reading “Shocking FDA TPSAC Meeting on PMI General Snus modified risk application”
FDA should consider the significant public health issues, especially for youth, created by PMI co-marketing of its Swedish Match General Snus and ZYN oral nicotine products and not reauthorize modified risk claims for General Snus
My colleagues at UCSF and I submitted this comment to the FDA Tobacco Products Scientific Advisory Committee opposing extension of PMI’s current authorization to make modified risk claims because its co-marketing with its ZYN nicotine pouch is fundamentally misleading. TPSAC is holding a meeting to discuss the modified risk request on June 26, 2024. AContinue reading “FDA should consider the significant public health issues, especially for youth, created by PMI co-marketing of its Swedish Match General Snus and ZYN oral nicotine products and not reauthorize modified risk claims for General Snus”
FDA should not renew its authorization allowing PMI to claim modified risk for its Swedish Match General Snus
My colleagues at UCSF and Stanford and I submitted this comment to the FDA Tobacco Products Scientific Advisory Committee opposing extension of PMI’s current authorization to make modified risk claims. (The committee is holding a meeting to discuss the application on June 26, 2004.) A PDF of the comment is here. (It will be submittedContinue reading “FDA should not renew its authorization allowing PMI to claim modified risk for its Swedish Match General Snus”
Cannabis associated with bad COVID-19 outcomes, like tobacco
Many studies have shown that current and past tobacco use is associated with poorer outcomes among people infected with COVID-19. Now Nicholas Griffin and colleagues have published a large well-done study showing that cannabis use is also associated with poorer outcomes among people who have developed COVID-19. The collected data on cannabis and tobacco useContinue reading “Cannabis associated with bad COVID-19 outcomes, like tobacco”
Implications of new RCT showing similar effects on quitting for nicotine e-cigs vs varenicline
Almost all the randomized controlled trials of e-cigarettes as clinical interventions for smoking cessation have compared e-cigarettes to nicotine replacement therapy. Varenicline, which is a prescription medication that works by blocking nicotine receptors rather than replacing the nicotine that cigarettes provide, is more effective than NRT. Anna Tsiku and colleagues new paper “Electronic Cigarettes vsContinue reading “Implications of new RCT showing similar effects on quitting for nicotine e-cigs vs varenicline”
English vaping reverses nicotine decline
In England, the country that has most aggressively embraced e-cigarettes, authorities have long minimized the effects of e-cigarettes on youth and argued that they were improving public health by attracting smokers or displacing cigarette use. Now Harry Tattan-Birch and colleagues have blown those arguments away. Their May 23, 2024 paper Trends in vaping and smokingContinue reading “English vaping reverses nicotine decline”
FDA did the right thing when it withdrew its 2022 Juul marketing denial order; it should finish the job quickly by prohibiting Juul on solid grounds
On June 6, 2024, two years after the FDA issued, then suspended its Marketing Denial Order for Juul e-cigarettes based on narrow toxicology issues, FDA formally withdrew the MDO. This does not mean that the FDA has authorized Juul for sale in the US, it just lets FDA start over in its assessment of whetherContinue reading “FDA did the right thing when it withdrew its 2022 Juul marketing denial order; it should finish the job quickly by prohibiting Juul on solid grounds”
Stanton Glantz blog 