More information on how ecigs increase cardiovascular disease risk

The evidence that e-cigarette use is associated with increased cardiovascular disease keeps accumulaing, together with studies on the specific pathophysiological mechanisms through which e-cigarette use increases disease risk. The recent review by Huiqi Zong, Zhekai Hu and colleagues, Electronic cigarettes and cardiovascular disease: epidemiological and biological links, is the most recent summary of this evidence.Continue reading “More information on how ecigs increase cardiovascular disease risk”

FDA needs to reconsider its promotion of the “continuum of risk” for e-cigarettes

As of February 22, 2024, the FDA was continuing to embrace the idea that there is a “continuum of risk” with combusted tobacco as the riskiest and e-cigarettes being substantially less risky. As a result, FDA promotes e-cigarettes as a way for smokers to reduce risk. This view is based on the fact that e-cigarettesContinue reading “FDA needs to reconsider its promotion of the “continuum of risk” for e-cigarettes”

Cannabis use linked to increase in heart attack and stroke risk

Many people think cannabis is “medicine” and so ignore its heath effects. Abra Jeffers, Amy Byers, Salome Keyhani and I just published Association of cannabis use with cardiovascular outcomes among US adults in the Journal of the American Heart Association that found that cannabis use is associated with adverse cardiovascular events with heavier use (moreContinue reading “Cannabis use linked to increase in heart attack and stroke risk”

E-cigs have similar risks to cigs for some diseases and nearly as high for others. Dual use riskier than smoking alone

It is an article of faith among e-cigarette advocates that they are substantially less risky than cigarettes. Rather than being based on the actual associations between e-cigarette use and disease, this belief is based on the fact that e-cigarettes do not burn tobacco, so avoid the toxic combustion products that cigarettes produce. In recent years,Continue reading “E-cigs have similar risks to cigs for some diseases and nearly as high for others. Dual use riskier than smoking alone”

Banning menthol leads a quarter of menthol smokers to quit

The two justifications for the FDA’s proposed product standard prohibiting menthol cigarettes and cigars are (1) it will reduce youth initiation, and (2) it will help menthol smokers to quit. Now Sarah Mills and colleagues have published a review and meta-analysis of the effects of menthol bans around the world, The Impact of Menthol CigaretteContinue reading “Banning menthol leads a quarter of menthol smokers to quit”

Relevant to COP10: Pharmaceuticalisation as the tobacco industry’s endgame

Yogi Hendlin, Eileen Han and Pam Ling’s new paper Pharmaceuticalisation as the tobacco industry’s endgame provides a detailed analysis of how the multinational tobacco companies have developed and used the companies efforts to reposition themselves a source for “clean” nicotine while simultaneously maintaining and expanding their sales of cigarettes and other “traditional” tobacco products whereContinue reading “Relevant to COP10: Pharmaceuticalisation as the tobacco industry’s endgame”

COP10 delegates need to base decisions on latest e-cig evidence, not the same old studies e-cig advocates promote

In the lead up to the WHO Framework Convention on Tobacco Control Tenth Conference of the Parties that starts today, advocates for e-cigarettes and other “reduced harm” tobacco products have been busy again arguing that delegates should embrace these products. In reviewing some of this material, I have been struck by the fact that theirContinue reading “COP10 delegates need to base decisions on latest e-cig evidence, not the same old studies e-cig advocates promote”

First 280,000 Juul documents publicly available, millions more to come

One of the key provisions of North Carolina’s 2021 settlement with Juul was that the documents produced in litigation would be made available to the public. The settlement required that the documents be made available through a depository run by a North Carolina university. To accomplish this, the University of North Carolina at Chapel Hill University LibrariesContinue reading “First 280,000 Juul documents publicly available, millions more to come”

Replacing 50% of cigs with ecigs or HTP had no lung benefit

E-cigarette advocates and tobacco harm reduction advocates, as well as the FDA, have long promoted a 50% reduction in cigarette smoking as a positive outcome when assessing the value of e-cigarettes (recent example). The FDA’s use of this benchmark is particularly surprising because in 2021 FDA scientists published a meta-analysis of the effects of smokers reducingContinue reading “Replacing 50% of cigs with ecigs or HTP had no lung benefit”

Cochrane Collaborative concludes that e-cigs as medicines help a few people shop smoking (again); still ignoring differences between medicines and consumer products as well as dual use

On January 8, 2024, the Cochrane Collaborative published yet another meta-analysis of randomized controlled trials concluding that e-cigarettes help a few people stop smoking. While industry and other pro-e-cigarette interests will make a big deal of this, the fact is that there is nothing new here. Here is their primary conclusion: There is high certaintyContinue reading “Cochrane Collaborative concludes that e-cigs as medicines help a few people shop smoking (again); still ignoring differences between medicines and consumer products as well as dual use”